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MELATONIN Sublingual Spray. You'll want it on your nightstand NOW! It is a food supplement in spray format formulated with liposomal melatonin. Melatonin helps induce sleep and contributes to relieving the subjective symptoms of jet lag. Fast action: the sublingual spray format, to be sprayed under the tongue, allows the direct incorporation of melatonin into the bloodstream, increasing its bioavailability and therefore its effect.